Table 5 Details of meiotic segregation patterns of embryos from the two reciprocal Y-autosome translocation carriers following alternate or adjacent- 1 separation
Mode of segregation | Embryo characterization with respect to the translocation | Combination of chromosomes | Embryos possessing the combination of the segregation mode for the chromosomal abnormality | Observed no. of embryos | Expected no. of embryos | Statistical Significance | |
|---|---|---|---|---|---|---|---|
t (Y;4) | t (Y;16) | ||||||
Alternate segregation | Normal Female | X and 4/16 | 7 embryos | 7 embryos | 14 | 8 | Deviation from 1:1 ratio, P = 0.003 |
Balanced Male | der Y and der 4/16 | 1 embryo | 1 embryo | 2 | 8 | ||
Adjacent −1 | Unbalanced Male | der Y and 4/16 | 5 embryos | 4 embryos | 9 | 5 | Deviation from 1:1 ratio, P = 0.011 |
Unbalanced Male | X and der 4/16 | 0 | 1 embryo | 1 | 5 | ||