Table 4 Summary of the follow up results of embryos from three PGD cycles performed for couple B with a male karyotype 46,X,t(Y;16)(q12;q13)
PGD cycle no./ Embryo no. | Follow up method | Day 6 Follow up result (Diagnostic result where follow up result not available) | Meiotic segregation (stage determined) | Chromosomes contributed by carrier parent | Embryo grade on follow up |
|---|---|---|---|---|---|
C1 E1 | FISH | Normal female | Alternate (follow up) | X and 16 | cavitating morula |
C1 E2 | FISH | No result | No result | No result | pre-morula |
C1 E3 | FISH | Male balanced for the translocation | Alternate (follow up) | der Y and der 16 | blastocyst |
C1 E4 | FISH | Abnormal | Unknown (follow up) | - | blastocyst |
C1 E5 | FISH | Male unbalanced for the translocation | Adjacent-1 (follow up) | der Y and 16 | blastocyst |
C1 E6 | FISH | Female unbalanced for the translocation | Adjacent-1 (follow up) | X and der 16 | blastocyst |
C1 E7 | n/a | Embryo transferred (normal female embryo) | Alternate (diagnosis) | X and 16 | blastocyst |
C1 E8 | FISH | Male unbalanced for the translocation | Adjacent-1 (follow up) | der Y and 16 | blastocyst |
C2 E1 | n/a | Embryo transferred (normal female embryo) | Alternate (diagnosis) | X and 16 | blastocyst |
C2 E2 | n/a | No result (Male unbalanced for the translocation) | Adjacent-1 (diagnosis) | der Y and 16 | blastocyst |
C3 E1 | aCGH | Normal Female | Alternate (follow up) | X and 16 | blastocyst |
C3 E2 | n/a | Embryo transferred (normal female embryo) | Alternate (diagnosis) | X and 16 | blastocyst |
C3 E3 | aCGH | Female embryo with additional aneuploidy | Alternate (follow up) | X and 16 | blastocyst |
C3 E4 | aCGH | Male unbalanced for the translocation with additional aneuploidy | Adjacent-1 (assumed) (follow up) | der Y and 16 | blastocyst |
C3 E5 | aCGH | Female embryo with additional aneuploidy | Alternate (follow up) | X and 16 | blastocyst |