Fig. 8
From: Inherent variability of cancer-specific aneuploidy generates metastases
Cellular morphologies and karyotypes of pancreatic cancer A13-B (a, b) and of two corresponding metastases, a pancreatic metastasis A13-A (c, d) and a liver metastasis A13-D (e, f). The comparisons show once more that the primary cancer A13-B and the corresponding metastases A13-A and A13-D have similar, but distinct cell morphologies (a, c, e) and karyotypes (b, d, f). The primary cancer and both metastases have hyper-diploid karyotypes with similar numbers of chromosomes and of aneusomies. The primary and the two metastases differ from each other in the total numbers of chromosomes and in the structures of some individual marker chromosomes see Tables 1 and 2). The cells were propagated and karyotyped as described for Fig. 2 [103]