Fig. 6

Cellular morphologies and karyotypes of colon cancer SW-480 (a, b) and of a corresponding metastasis SW-620 (c, d). The comparisons show once more that the primary cancer SW-480 and the corresponding metastasis SW-620 have similar, but distinct cell morphologies (a, c) and karyotypes (b, d). Both primary cancer and metastasis have hyper-diploid karyotypes with similar numbers of chromosomes and of aneusomies. They also differ from each other in the total numbers of chromosomes and in the structures of some marker chromosomes (see Tables 1 and 2). We adduce evidence in the text that both SW-480 and SW-620 are probably both metastases of an unknown primary. The cells were propagated and karyotyped as described for Fig. 2