Fig. 4
From: Inherent variability of cancer-specific aneuploidy generates metastases
Cellular morphologies and karyotypes of liver cancer H2P (a, b) and a corresponding portal vein metastasis H2M (c, d). The comparisons show that the primary cancer H2P and the corresponding metastasis H2M have similar, but distinct cell morphologies (a, c) and karyotypes (b, d). Both primary cancer and metastasis have hyper-triploid karyotypes with similar numbers of chromosomes and aneusomies, and both lack intact chromosome 4. They differ from each other in the total numbers of chromosomes and in the structures of some marker chromosomes (see Tables 1 and 2). The cells were propagated and karyotyped as described for Fig. 2