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Table 1 Frequencies of MMC- and BLM-induced MN with centromeric and whole-chromosome painting signals

From: Comparative analysis of individual chromosome involvement in micronuclei induced by mitomycin C and bleomycin in human leukocytes

Chromosome number

Total number of MN

Number (%) of MN with cep signals

Number (%) of MN with wcp signals

 

MMC-induced MN

8

1,262

19 (1.51)

31 (2.46)

15

1,262

16 (1.27)

32 (2.54)

20

1,262

7 (0.55)

16 (1.27)

 

BLM-induced MN

1

1,387

14 (1.01)

114 (8.22)

9

1,387

10 (0.72)

65 (4.69)

16

1,387

10 (0.72)

35 (2.52)

  1. cep centromeric, MMC mitomycin C, BLM bleomycin, MN micronuclei, wcp whole-chromosome painting
  2. Implementation of cep and wcp probes for the studied chromosomes revealed frequencies of involvement of chromosomes 8, 15 and 20 in MMC-induced MN and chromosomes 1, 9 and 16 in BLM-induced MN in human leukocytes