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Table 1 Summary of rapid aCGH results for 86 embryos from 8 patients accepted for fresh single embryo transfer (SET) and 58 embryos from 13 patients choosing vitrified SET or double embryo transfer (DET)

From: A pilot proof-of-principle study to compare fresh and vitrified cycle preimplantation genetic screening by chromosome microarray and next generation sequencing

Case no.

Age of patient

No. of embryos for aCGH

SET or DET

Chemical pregnancy (+hCG)

Outcome

Total

WGA failure

Euploid

Aneuploid

I. Fresh SET

1

29

10

0

1

9

SET

Yes

Live birtha (at GA = 37+6 weeks)

2

33

9

0

4

5

SET

Yes

Abortion (at GA = 5 weeks)

3

34

14

0

3

11

SET

No

4

34

14

0

6

8

SET

Yes

Ongoing pregnancy (GA = 37 weeks)

5

37

13

0

7

6

SET

Yes

Ongoing pregnancy (GA = 13 weeks)

6

34

9

0

5

4

SET

Yes

Abortion (at GA = 4 weeks)

7

37

9

0

8

1

SET

Yes

Ongoing pregnancy (GA = 16 weeks)

8

31

8

0

6

2

SET

Yes

Ongoing pregnancy (GA = 7 weeks)

Overall

 

86

0

40

46

   

II. Vitrified ET

1

41

3

0

1

2

SET

Yes

Live birth (at GA = 39 weeks)

2

40

4

0

1

3

SET

Yes

Termination (acardiac monster) (at GA = 14+4 week)

3

34

4

0

3

1

SET

Yes

Ongoing pregnancy (GA = 19+4 week)

4

39

5

0

1

4

SET

Yes

Ongoing pregnancy (GA = 22 week)

5

42

3

0

2

1

DET

No

6

37

6

0

5

1

DET

Yes

Live birth (at GA = 38 weeks)

7

36

5

0

4

1

DET

Yes

Live birth (at GA = 37 weeks)

8

37

5

0

2

3

DET

Yes

Abortion (at GA = 8+3 weeks)

9

42

5

0

2

3

DET

No

10

37

3

0

3

0

DET

Yes

Ongoing pregnancy (GA = 16 week)

11

34

5

0

5

0

DET

No

12

34

5

0

3

2

DET

Yes

Abortion (at GA = 10+6 weeks)

13

35

5

2

2

1

DET

Yes

Ongoing pregnancy (GA = 12+3 weeks)

Overall

 

58

2

34

22

   
  1. aSingle birth (3040 g; AS 8 > 9) by C-section due to breech presentation
  2. WGA whole genome amplification, GA gestational age