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Table 1 Summary of rapid aCGH results for 86 embryos from 8 patients accepted for fresh single embryo transfer (SET) and 58 embryos from 13 patients choosing vitrified SET or double embryo transfer (DET)

From: A pilot proof-of-principle study to compare fresh and vitrified cycle preimplantation genetic screening by chromosome microarray and next generation sequencing

Case no. Age of patient No. of embryos for aCGH SET or DET Chemical pregnancy (+hCG) Outcome
Total WGA failure Euploid Aneuploid
I. Fresh SET
1 29 10 0 1 9 SET Yes Live birtha (at GA = 37+6 weeks)
2 33 9 0 4 5 SET Yes Abortion (at GA = 5 weeks)
3 34 14 0 3 11 SET No
4 34 14 0 6 8 SET Yes Ongoing pregnancy (GA = 37 weeks)
5 37 13 0 7 6 SET Yes Ongoing pregnancy (GA = 13 weeks)
6 34 9 0 5 4 SET Yes Abortion (at GA = 4 weeks)
7 37 9 0 8 1 SET Yes Ongoing pregnancy (GA = 16 weeks)
8 31 8 0 6 2 SET Yes Ongoing pregnancy (GA = 7 weeks)
Overall   86 0 40 46    
II. Vitrified ET
1 41 3 0 1 2 SET Yes Live birth (at GA = 39 weeks)
2 40 4 0 1 3 SET Yes Termination (acardiac monster) (at GA = 14+4 week)
3 34 4 0 3 1 SET Yes Ongoing pregnancy (GA = 19+4 week)
4 39 5 0 1 4 SET Yes Ongoing pregnancy (GA = 22 week)
5 42 3 0 2 1 DET No
6 37 6 0 5 1 DET Yes Live birth (at GA = 38 weeks)
7 36 5 0 4 1 DET Yes Live birth (at GA = 37 weeks)
8 37 5 0 2 3 DET Yes Abortion (at GA = 8+3 weeks)
9 42 5 0 2 3 DET No
10 37 3 0 3 0 DET Yes Ongoing pregnancy (GA = 16 week)
11 34 5 0 5 0 DET No
12 34 5 0 3 2 DET Yes Abortion (at GA = 10+6 weeks)
13 35 5 2 2 1 DET Yes Ongoing pregnancy (GA = 12+3 weeks)
Overall   58 2 34 22    
  1. aSingle birth (3040 g; AS 8 > 9) by C-section due to breech presentation
  2. WGA whole genome amplification, GA gestational age