Patient | Age (y) | Sex | MS-MLPA | CMA, Chromosome 15 | Angelman Syndrome Features | Prader-Willi Syndrome Features | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Microcephaly | Speech Delay | Gait Ataxia | Seizures | Happy Disposition | Hypotonia | Growth Failure | Obesity | Hyperphagia | Hypogonadism | |||||
1 | 4 | M | Mosaicism for maternal copy | Hmz 15 | -- | -- | Y | N | -- | -- | -- | N | -- | -- |
2 | 11 | F | Mosaicism for maternal copy | Partial hmz 15 | -- | Y | -- | -- | -- | Y | -- | -- | -- | -- |
3 | 3 | M | Mosaicism for maternal copy | Normal | Y | Y | Y | Y | N | Y | N | N | N | N |
4 | 6 | F | Mosaicism for maternal copy | Normal | N | Y | N | N | Y | Y | N | N | N | N |
5 | 6 | F | Mosaicism for maternal copy | Normal | -- | -- | -- | Y | Y | -- | -- | -- | -- | -- |
6 | 6 | M | Mosaicism for maternal copy | Normal | -- | Y | -- | N | -- | -- | -- | Y | Y | -- |
7 | 2 | F | Mosaicism for maternal copy | Normal | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
8 | 8 | M | Mosaicism for maternal copy | Normal | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
9 | 9 | M | Mosaicism for maternal copy | Normal | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
10 | 10 | M | Mosaicism for maternal copy | Normal | Y | Y | Y | -- | Y | -- | -- | N | Y | -- |