Table 3 Sixteen differentially expressed genes in the group of Wilms tumours compared to differentiated kidneys which exhibited a concordant pattern of copy number alteration (CNA)
From: Genomic imbalances pinpoint potential oncogenes and tumor suppressors in Wilms tumors
Gene name | Fold change | Type of CNA |
|---|---|---|
CNKSR1 | −2.30* | 1p36.12p36.11 deletion |
MAN1C1 | −7.37** | 1p36.12p36.11 deletion |
PAQR7 | −10.71** | 1p36.12p36.11 deletion |
CHD1L | 3.18** | 1q21.1q23.2 gain |
CRABP2 | 31.59** | 1q21.1q23.2 gain |
GJA8 | 25.48* | 1q21.1q23.2 gain |
MEX3A | 10.28** | 1q21.1q23.2 gain |
MLLT11 | 14.04** | 1q21.1q23.2 gain |
DNMT3A | 2.42** | 2p25.3p11.2 gain |
INPP5D | −2.56* | 2q37 deletion |
AHR | −9.62** | 7p14.1p12.2 deletion |
SOSTDC1 | −21.39** | 7p14.1p12.2 deletion |
TWIST1 | −3.26* | 7p14.1p12.2 deletion |
BBOX1 | −39.84* | 11p13p12 homozygous loss in one WT |
FIBIN | −8.10* | 11p13p12 homozygous loss in one WT |
PLCG2 | −8.96* | 16q22.1q24.3 deletion |