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Fig. 2 | Molecular Cytogenetics

Fig. 2

From: Primary and recurrent diffuse astrocytomas: genomic profile comparison reveals acquisition of biologically relevant aberrations

Fig. 2

Molecular cytogenetic and epigenetic analyses of the three lesions of case no. 1. a Results of a SNP array for each lesion, with the selection of three chromosomes, in which additional changes were detected. Red bars indicate deletions of a chromosomal region. Green bars represent amplifications, and CN-LOH is marked with gray boxes. b Result of I-FISH analysis confirming and extending the SNP array findings. 1,3, deletion of 19q13 probe; 2, amplification of 13q34; 4, multiple amplifications of 13q34 probe; 5, amplification of 13q34 with monoallelic loss of the RB1 gene; and 6, trisomy of chromosome 7

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