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Fig. 2 | Molecular Cytogenetics

Fig. 2

From: Preferential Y-Y pairing and synapsis and abnormal meiotic recombination in a 47,XYY man with non obstructive azoospermia

Fig. 2

Sex chromosome pairing and recombination in the 47, XYY patient. Representative pachytene spermatocytes immunostained for CREST (Blue), SYCP3 (Red) and MLH1 (Green). a Two Y chromosomes partially paired and associated with X chromosome. There is no recombination on the sex chromosomes. c Two Y chromosomes partially paired and associated with chromosome X. Notably there is a recombination focus on the short arm of Y bivalent. e Two Y chromosomes completely paired and associated with X chromosome at the end of short arms. Notably there is no recombination on the sex chromosomes. g Two Y chromosomes completely paired and associated with chromosome X. Notably there is a recombination focus on the short arm of Y bivalent. b, d, f and h are the schematic configurations of the sex chromosomes from the cell shown in a, c, e and g, respectively

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