Genetic feature | Number of patients | Median TTT (months) | Median OS (months) | ||
---|---|---|---|---|---|
TTT | OS | ||||
IGHV status | unmutated | 24 | 25 | 18 | 110 |
mutated | 15 | 15 | 89 | Not reached | |
P-value | p = 0,003 | p = 0,003 | |||
13q14 deletion | monoallelic | 20 | 21 | 19 | 140 |
biallelic | 19 | 19 | 53 | 148 | |
P-value | p = 0,203 | p = 0,511 | |||
13q14 deletion without delTP53 | monoallelic | 20 | 21 | 19 | 140 |
biallelic | 16 | 16 | 60 | Not reached | |
P-value | p = 0,099 | p = 0,237 | |||
13q14 deletion without del TP53 and del ATM | monoallelic | 14 | 14 | 19 | 140 |
biallelic | 14 | 14 | 60 | Not reached | |
P- value | p = 0,141 | p = 0,444 | |||
13q14 deletion | with Rb deletion | 16 | 16 | 21 | 140 |
without Rb deletion | 23 | 24 | 30 | 148 | |
P- value | p = 0,426 | p = 0,942 |