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Table 5 Statistical analysis of 40 CLL/SLL patients

From: Monoallelic and biallelic deletions of 13q14 in a group of CLL/SLL patients investigated by CGH Haematological Cancer and SNP array (8x60K)

Genetic feature

 

Number of patients

Median TTT (months)

Median OS (months)

TTT

OS

IGHV status

unmutated

24

25

18

110

mutated

15

15

89

Not reached

P-value

  

p = 0,003

p = 0,003

13q14 deletion

monoallelic

20

21

19

140

biallelic

19

19

53

148

P-value

  

p = 0,203

p = 0,511

13q14 deletion without delTP53

monoallelic

20

21

19

140

biallelic

16

16

60

Not reached

P-value

  

p = 0,099

p = 0,237

13q14 deletion without del TP53 and del ATM

monoallelic

14

14

19

140

biallelic

14

14

60

Not reached

P- value

  

p = 0,141

p = 0,444

13q14 deletion

with Rb deletion

16

16

21

140

without Rb deletion

23

24

30

148

P- value

  

p = 0,426

p = 0,942

  1. TTT time to treatment, OS overall survival