Chromosomal copy number analysis on chorionic villus samples from early spontaneous miscarriages by high throughput genetic technology

Table 4 Origin analysis of 3 cases with small-size segmental imbalances by FISH

No.	Copy number variants	FISH test			Parental origin
No.	Copy number variants	Probe^a	Paternal	Maternal	Parental origin
C0012	-(2q37.3-qter)(4.6 M);	6p SG; 6q SO	Normal	Normal	De novo
C0012	+(6q23.2-qter)(36.1 M)	6p SG; 6q SO	Normal	Normal	De novo
C0044	-(6q25.3-qter)(12.5 M);	6p SG; 6q SO	Carrier	Normal	Paternal
C0044	+(10q26.11-qter)(13.8 M)	6p SG; 6q SO	Carrier	Normal	Paternal
C0146	+(9q34.11-qter)(9.2 M);	14q SO	Carrier	Normal	Paternal
C0146	-(14q32.13-qter)(14.8 M)	14q SO	Carrier	Normal	Paternal

^aFISH test was performed on the metaphase of lymphocytes using telomeric probes. SG spectrum of green, SO spectrum of orange. Carrier, reciprocal balanced translocation carrier

ISSN: 1755-8166