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Fig. 2 | Molecular Cytogenetics

Fig. 2

From: Masked inv dup(22)(q11.23), tetrasomy 8 and trisomy 19 in a blast crisis-chronic myeloid leukemia after interrupted Imatinib-treatment

Fig. 2

Karyotype and chromosomal aberrations were confirm ed using molecular cytogenetic approaches. a FISH using probes for BCR (green) and ABL (red) showed one red signal on normal chromosome 9; three green signals, one on normal chromosome 22 and two on der(22); BCR/ABL1 fusion on der(9) with absent of an ABL1 signal on der(22). b The application of MCB (22) characterized the inv dup(22)(q11.23) comprehensively. c FISH using alpha satellite probe for chromosomes 14 and 22 together revealed two centromers on der(22). Abbreviations: # = chromosome; der = derivative chromosome

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Molecular Cytogenetics

ISSN: 1755-8166