Fig. 3
From: Copy number variants prioritization after array-CGH analysis – a cohort of 1000 patients
Class II de novo and inherited imbalances. In 82 % of the inherited CNVs had a genomic size ranging from 1.985 kb to 600 kb, against 28 % of the de novo, while 51 % of the de novo imbalances had a genomic size ranging from 1 to 5 Mb. The higher the genomic size of the imbalance, the lower the probability of being inherited. Our data show a significant association (χ 2(1) = 44.456; p < 0.001) between de novo imbalances and sizes above 500 kb and between inherited imbalances and sizes below 500 kb – dashed line