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Fig. 2 | Molecular Cytogenetics

Fig. 2

From: Karyotype alteration generates the neoplastic phenotypes of SV40-infected human and rodent cells

Fig. 2

Phenotypes of human mesothelial cells three weeks after infection by SV40 compared to an uninfected control. A subconfluent culture of human mesothelial cells was infected with SV40 at a multiplicity of 10. In parallel an uninfected culture was maintained under the same conditions (see text). a A 120X magnification of the infected culture three weeks after infection shows highly increased cell density and “pre-transformed” cell morphologies [13], compared to the uninfected control shown in (b). It follows that SV40 transforms the morphology and raises the density of cultures of mesothelial cells shortly after infection

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