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Fig. 1 | Molecular Cytogenetics

Fig. 1

From: A rare coincidence of different types of driver mutations among uterine leiomyomas (UL)

Fig. 1

Cytogenetic and molecular analysis of uterine leiomyomas. a-d representative G-banded karyotypes of four uterine leiomyomas. a tumor 709/1, Karyotype: 45,XX,del(3)(q24q25.33),del(7)(q11.2),add(9)(q34),-15,der(17)t(15;17)(q?22;p?11.2)[3]/46,XX[3]. Of ten additional hypodiploid metaphases seven showed structural abnormalities and losses and three only losses of chromosomes. In contrast to the structural abnormalities, none of the losses observed were clonal. b tumor 709/2, karyotype: 43 ~ 46,XX,del(1)(p34),der(2),-11 + mar. c tumor 709/3, karyotype: 46,XX[22]. d tumor 709/4, karyotype: 46,XX[17]. e mutation of MED12 (c.131G > A) of tumor 709/2

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