Fig. 6From: Trisomy Xp and partial tetrasomy Xq resulting from gain of a rearranged X chromosome in a female fetus: pathogenic or not?Proposed mechanism for the origin of the extra rearranged X chromosome. a: Interchromatid exchange in maternal meiosis, b: formation of a dicentric chromosome, loss of the acentric fragments, c: separation of two centromeres at anaphase resulting in breakage near one of the centromeres, d: inv dup(X) with del(X) and satellited Xq. Blue arrows indicate breakpointsBack to article page