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Fig. 1 | Molecular Cytogenetics

Fig. 1

From: Disomy 21 in spermatozoa and the paternal origin of trisomy 21 Down syndrome

Fig. 1

Examples of fluorescence in situ hybridisation (FISH) results, using two chromosome 21 specific probes (Vysis LSI 21 in red and Cytocell tel 21 in green). a Location of the probes near the end of the long arm of chromosome 21. Reproduced from [7] b A normal spermatozoon showing one dual chromosome 21-specific signal in combination with one chromosome 18 control probe signal (Vysis CEP18 in pink). c A spermatozoon showing two dual chromosome 21-specific signals (red and green) together with one chromosome 18 signal, therefore recorded as disomy 21.

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