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Table 1 Results of FISH on metaphase spreads from the proband

From: Language impairment in a case of a complex chromosomal rearrangement with a breakpoint downstream of FOXP2

7p breakpoint (α/α’)
BAC Start (hg19) End (hg19) Cytogenetic band Localization in Proband
RP11-61 N24 20,748,162 20,919,479 7p21.1-p15.3 Derivative 11p
RP11-799 L23 20,810,041 21,001,537 7p21.1-p15.3 Split: derivative 7q, derivative 11p
RP11-97 L4 20,954,043 21,104,475 7p15.3 Split: derivative 7q, derivative 11p
7q breakpoint (β/β’)
BAC Start (hg19) End (hg19) Cytogenetic band Localization in Proband
RP11-259A16 114,374,055 114,528,369 7q31.1-31.2 Derivative 11p
RP11-1 N24 114,451,504 114,603,837 7q31.1-31.2 Split: derivative 7q, derivative 11p
RP11-243D16 114,556,605 114,733,501 7q31.1-31.2 Derivative 7q
RP11-259A16 114,374,055 114,528,369 7q31.1-31.2 Derivative 11p
7q Breakpoint (γ/γ’)
BAC Start (hg19) End (hg19) Cytogenetic band Localization in Proband
RP11-7B9 93,714,463 93,884,065 7q21.3 Derivative 7p
RP11-248I13 93,933,453 94,094,489 7q21.3 Derivative 11p
11p breakpoint (δ/δ’)
BAC Start (hg19) End (hg19) Cytogenetic band Localization in Proband
RP11-63D14 38,455,222 38,604,308 11p12 Derivative 7p
RP11-81O6 38,601,145 38,749,858 11p12 Split: derivative 7q, derivative 11p
RP11-99H2 38,621,572 38,794,051 11p12 Derivative 11p