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Fig. 1 | Molecular Cytogenetics

Fig. 1

From: Evaluation of multiplex ligation dependent probe amplification (MLPA) for identification of acute lymphoblastic leukemia with an intrachromosomal amplification of chromosome 21 (iAMP21) in a Brazilian population

Fig. 1

Representative MLPA data shown as screen shots from the Gene-Marker 2.2.0 analysis software. a. MLPA electropherograms of cord blood (CB) DNA (upper panel) compared to DNA from P4 (lower panel). Differences in peaks heights suggest altered dosages of corresponding exons depicted below. b. MLPA scatter plots for CB DNA (left panel) compared to P4 DNA (right panel). Reference probes (blue points) and test probes (green points) are within the normal range (located between green lines) for the CB sample, while test probes (red points) appear elevated for P4

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Molecular Cytogenetics

ISSN: 1755-8166