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Table 4 CTs exhibiting radial repositioning in activated lymphocytes compared to resting lymphocytes

From: Chromosome territory repositioning induced by PHA-activation of lymphocytes: A 2D and 3D appraisal

2D repositioning

Male Subject

Female Subject

CTs

Movement

CTs

Movement

1, 6, 14, 16, 20

Less interior

1, 15, 19

Less interior

4, 5, 9

Interior to intermediate

11

Interior to intermediate

2

Intermediate to periphery

7

Interior to periphery

X

Intermediate to interior

-

-

3D repositioning

Male Subject

Female Subject

CTs

Movement

CTs

Movement

11, 14, 15, 16, 17, 19

More peripheral

11, 16, 19, X

More peripheral

  1. CTs involved in statistical significant radial repositioning between resting and activated lymphocytes in both the male and female subject, as determined by 2D and 3D approaches. 2D radial repositioning was determined using the χ 2 goodness-of-fit test (p < 0.05). The direction of the repositioning movement was determined by comparing the radial distribution of CTs in each subject in resting and activated lymphocytes (Fig. 1). 3D radial repositioning was determined using the two-tailed, paired t-test (p < 0.05). The direction of the repositioning movement was determined based on the distance to the nuclear edge in activated lymphocytes compared to resting lymphocytes