Chromosome territory repositioning induced by PHA-activation of lymphocytes: A 2D and 3D appraisal

Table 1 Random/nonrandom organization status of all 24 CTs in 2D resting and activated lymphocytes

CT	Male	Female	Male	Female
	-PHA	-PHA	+PHA	+PHA
1	NR	NR	NR	NR
2	NR	NR		NR
3		NR
4	NR	NR		NR
5	NR
6	NR	NR	NR	NR
7	NR	NR
8	NR	NR	NR	NR
9	NR	NR
10	NR	NR	NR	NR
11	NR	NR
12	NR	NR	NR	NR
13		NR
14	NR	NR	NR	NR
15	NR	NR	NR	NR
16	NR	NR	NR	NR
17	NR	NR	NR	NR
18	NR
19	NR	NR	NR	NR
20	NR	NR	NR	NR
21	NR	NR	NR	NR
22	NR	NR	NR	NR
X	NR	NR	NR	NR
Y*	NR	-		-

Presents the status (nonrandom or random) of CT organization for all chromosomes in resting (-PHA) and activated (+PHA) lymphocytes for each participant enrolled in this study. A minimum of 100 cells were captured and analyzed per CT, per subject in both resting (-PHA) and activated (+PHA) lymphocytes. The χ ² goodness of fit test (d.f: 4) was utilized to determine whether the 2D radial distribution of each CT was random (p > 0.05) or nonrandom (p < 0.05). Nonrandom organization is denoted by NR (p < 0.05), random organization (p > 0.05) is denoted by blank boxes. *Data for the Y chromosome is only available from the male subject

ISSN: 1755-8166