Fig. 1

Statistically positive loci for log2 signal ratios in 48 sets of CGH microarrays. The signal bias was tested at each probe site by a two-tailed t-test. Bars represent the chromosomal position and lengths represent the logarithmic value of the probability of rejecting the null hypothesis. As comparisons were repeated 1381 times, we applied the Bonferroni’s correction and decreased a statistical threshold from p = 0.05 to p = 0.05/1381 (−log p = 4.44). Within a positive candidate CNV locus, neighboring probe sites were merged and their probabilities were cumulated (Additional file 1: Table S2). Note: Data from chromosomes 17 and 21 are not shown because these did not include any positives