Fig. 2

Detailed view of gains and losses of chromosomes 9, 11, and X. a Chromosome 9. The heterozygous 4760 kb deletion includes a homozygous deletion of CDKN2A/B indicated by the decrease of the smooth signal to zero. The smaller heterozygous loss affects, amongst other genes, the 3’-end of PAX5. b Chromosome 11. The heterozygous deletion at 11p13 includes the 5’-end of KIAA1549L. c Chromosome X. The changes of the log2 ratios along the chromosome indicate a trisomy of the entire q-arm and a small part of the p-arm as well as loss of most of the p-arm, indicating the presence of an idic(X)(p11)