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Figure 1 | Molecular Cytogenetics

Figure 1

From: Partial tetrasomy of the proximal long arm of chromosome 15 in two patients: the significance of the gene dosage in terms of phenotype

Figure 1

Karyotype and FISH analysis. (a) Karyotype of Patient 1. illustrates the supernumerary chromosome 15. (b) FISH analysis of Patient 1. by using probes for UBE3A locus (red) at 15q11q13, D15Z1/CEP15 locus (cyan) at 15p11.2 and PML locus (green) at 15q22 illustrates the tetrasomy of chromosome 15q11q13. (c) Karyotype of Patient 2. illustrates the supernumerary chromosome 15. (d) FISH analysis of Patient 2. by using probes for UBE3A locus (red) at 15q11q13, D15Z1/CEP15 locus (cyan) at 15p11.2 and PML locus (green) at 15q22 illustrates the tetrasomy of chromosome 15q11q13

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