Figure 2

Cytogenetics results. A) Partial G-banding karyotype of proband (III-1): 45,XX,der(10)t(10;15)(q26.3;q11.2),-15 [red ovale]; B) Ideogram showing normal chromosomes 10 and 15, as well as derivative chromosome 10 of proband (III-1); C) FISH analysis of proband (III-1): ish del(15)(q11.2q11.2)(SNRPN-, PMLx2) [SNRP/red, PML/green]; D) Partial G-banding karyotype of the proband’s mother (II-2): 46,XX,t(10;15)(q26.3;q11.2) [red ovale]; E) Ideogram showing chromosomes 10, 15 and the balanced reciprocal translocation in the proband’s mother (II-2).