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Figure 1 | Molecular Cytogenetics

Figure 1

From: Subtelomeric multiplex ligation-dependent probe amplification as a supplement for rapid prenatal detection of fetal chromosomal aberrations

Figure 1

Identification of chromosomal rearrangements with karyotype analyses and MLPA. (A) Karyotype analysis showed a derived chromosome 21 (black arrow). Band analyses revealed the derived chromosome was longer than chromosome 21 and the two copies of chromosome 17 were normal. (B) MLPA results with probe P036-E2 (left) and P070-B2 (right). Probes targeting 17q25.3 (blue dot) were increased and the signals for 21q22.3 (red dot) were decreased, indicating unbalanced translocation with deletion of 21qter and duplication of 17qter.

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