Table 4 Result summary of the comparison analysis between grade 1/well differentiated HCCs and grade 2-4/moderately or poorly differentiated HCCs (Figure 3 A and B)
Region [hg19] | Cytoband location | Copy number | Region length (kb) | Grade 1 and well differentiated HCC (freq. %) | Grade 2–4 and moderately and poorly differentiated HCC (freq. %) | p-value | Number of genes | Sanger census cancer genes |
|---|---|---|---|---|---|---|---|---|
chr1:146,319,961-159,188,358 | q21.1 - q23.2 | Gain | 12,868 | 40 | 100 | 0.022 | 261 | BCL9, ARNT, TPM3, MUC1, NTRK1 |
chr8:46,967,935-67,313,267 | q11.1 - q13.1 | Gain | 20,345 | 0 | 60 | 0.044 | 76 | CHCHD7, TCEA1, PLAG1 |
chr11:113,937,346-114,144,024 | q23.2 | Gain | 207 | 60 | 0 | 0.022 | 1 (ZBTB16) | Â |
chr16:79,628,093-79,633,200 | q23.2 | Gain | 5 | 60 | 0 | 0.022 | 1 | MAF |