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Table 7 Regrouping of samples from Table 6 after doing additional i-FISH as suggested in Figure 2

From: Comprehensive chronic lymphocytic leukemia diagnostics by combined multiplex ligation dependent probe amplification (MLPA) and interphase fluorescence in situ hybridization (iFISH)

Results according to MLPA Adverse prognosis Intermediate prognosis Good prognosis “unfavorable” Good prognosis “favorable” No aberrations
Samples 1+, 2, 3+, 10, 12, 13, 14, 15, 16, 17, 18, 19, 24, 34, 35, 38, 39, 54, 58, 60+, 61, 63, 64, 65, 4, 5, 37, 62, 68 20, 21, 22, 23, 25, 26, 27, 28, 29, 30, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 55, 56, 66, 67 6, 7, 8, 9, 11, 31, 32, 33, 40, 41, 42, 59, 69 36, 57, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85
Number of samples per group (absolute) 24 5 25 13 18
Number of samples per group (percent) 28 6 30 15 21
  1. Samples marked with + have rea(14)(q32.33), thus they have to go to the adverse prognosis group. Samples with deletion of 13q14.2 and 13q14.3 detected by MLPA and/or deletion of 13q14.3 in ≥70% of the nuclei detected by iFISH go to unfavorable subgroup within good prognosis group. Figures printed not bold and not in italics are case numbers; figures printed bold and in italics are absolute numbers of samples or same numbers in percent.