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Table 4 Detailed results in samples with concordance of MLPA and routine iFISH results but mosaic rates below 40% according to iFISH

From: Comprehensive chronic lymphocytic leukemia diagnostics by combined multiplex ligation dependent probe amplification (MLPA) and interphase fluorescence in situ hybridization (iFISH)

Affected regions Genes Sample number iFISH mosaic [%]
del(11)(q22.3q22.3) ATM 14 23.5
del(11)(q22.3q22.3) ATM 15 24
del(11)(q22.3q22.3) ATM 16 11
del(13)(q14.3q14.3) DLEU1, DLEU2, MIR15A 1 30
del(13)(q14.3q14.3) DLEU1, DLEU2, MIR15A 2 18
del(13)(q14.3q14.3) DLEU1, DLEU2, MIR15A 4 20
del(13)(q14.3q14.3) DLEU1, DLEU2, MIR15A 14 34
del(13)(q14.3q14.3) DLEU1, DLEU2, MIR15A 17 20
del(17)(p13.1p13.1) TP53 1 16
del(17)(p13.1p13.1) TP53 12 21
del(17)(p13.1p13.1) TP53 18 19
del(17)(p13.1p13.1) TP53 19 36