Table 1 Summary of 99 aberrations as detected by MLPA and 146 ones as detected or confirmed by iFISH; samples contributing to the discordant results of MLPA and iFISH are marked with asterisk *, ** or ‘plus-sign’ ⁺

amp(2)(p24.3p24.3)

MYCN

3

3

amp(2)(p23.2 ~ 23.1p23.2 ~ 23.1)

ALK

3

3

del(6)(q21q21)

FYN

1

1

del(6)(q23.3q23.3)

MYB

2

2

del(6)(q25.1q25.1)

ESR1

1

1

del(6)(q27q27)

SMOC2

1

1

amp(6)(q27q27)

SMOC2

1⁺

0

amp(8)(q24.21q24.21)

MYC

1

1

t(9;22)(q34;q11)

BCR and ABL

n.a.

1

del(11)(q22.3q22.3)

ATM

12

14*

+12

ETV6, CCND2,

4

6*

MDM2

del(13)(q14.2q14.2)

RB1

10

11**

del(13)(q14.2q14.2)x2

RB1

1

10**

del(13)(q14.3q14.3)

DLEU1, DLEU2,

35

46*^/**

MIR15A

del(13)(q14.3q14.3)x2

DLEU1, DLEU2,

7

14**

MIR15A

del(14)(q32q32)

IGH

n.a.

13

rea(14)(q32.33) - > t(14;?)

IGH

n.a.

2

rea(14)(q32.33) - > ? + 14

IGH

n.a.

1

del(17)(p13.1p13.1)

TP53

9

10*

amp(17)(q25.1q25.2)

UNC13D

2

2

amp(18)(p11.21q11.21)

DCC

2⁺

1

amp(18)(q21.2q21.2)

RNMT

2⁺

1

amp(21)(q22.12q22.12)

RUNX1

2

2