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Figure 4 | Molecular Cytogenetics

Figure 4

From: Karyotypic evolutions of cancer species in rats during the long latent periods after injection of nitrosourea

Figure 4

Cellular morphologies of two rat mammary carcinomas and of four neoplastic clones evolved from rat hyperplasias in vitro. Cells of the rat mammary carcinomas RMT 47–3 and 37–2 and of four clonal neoplasias derived from mammary hyperlasias termed RMT-CN 65, RMT-CN 58, RMT-CN 54 and RMT-CN 61 were photographed in cell culture dishes at a magnification of 100x with a phase-contrast microscope. The following individualities were observed: (A) A dense monolayer of polygonal cells of the RMT 47–3 carcinoma, (B) Three-dimensional colonies of round and refractile cells of the carcinoma RMT 37–2 clone 1, (C) A dense monolayer of fusiform cells of the clonal neoplasia RMT-CN 65, (D) A three-dimensional multilayer of pleomorphic-round cells of the clonal neoplasia RMT-CN 58, (E) A relatively flat monolayer of fusiform, triangular cells of the clonal neoplasia RMT-CN 54, (F) A three-dimensional cell layer of elongated refractile cells of the clonal neoplasia RMT-CN 61.

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Molecular Cytogenetics

ISSN: 1755-8166