Figure 2
From: Partial and complete trisomy 14 mosaicism: clinical follow-up, cytogenetic and molecular analysis
Cytogenomic analysis A) Microarray analysis shows a partial trisomy 14 of the proximal region between 19.5 Mb and 21.3 Mb (arr 14q11.1q11.2(18,127,052-19,927,052) x 2~3). FISH with DNA BACs probes for 14q11.2 spectrum green and 14q32.33 spectrum orange shows: B) Metaphase with whole trisomy 14, each chromosome 14 with one green and one orange signals; C) Metaphase with del(14)(q11.2) lacking 14q32.33 orange signal. GTG-banded partial karyotype showing: D) +del(14)(q11.2) E) trisomy 14 and F) normal diploid chromosomes 14.