Figure 5From: Induction of polyploidy by nuclear fusion mechanism upon decreased expression of the nuclear envelope protein LAP2β in the human osteosarcoma cell line U2OS Duplicated and single chromosomal markers in LAP2β KD karyotypes. Representative karyotypes from LAP2β KD clone 1 (A) and two sub-clones of untreated (B, C) U2OS cells (U2OS-1 and U2OS-2, respectively). The frames are around chromosomal markers: A1-A7 (yellow) which are common in all the sub-clones and are duplicated upon LAP2β KD; B-E (green) which are typical only for one sub-clone and stay as single in LAP2β KD cells. Chromosome numbers (white) are indicated.Back to article page