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Figure 2 | Molecular Cytogenetics

Figure 2

From: Characterization of a complex chromosomal rearrangement using chromosome, FISH, and microarray assays in a girl with multiple congenital abnormalities and developmental delay

Figure 2

FISH results with whole-chromosome painting (WCP) for chromosomes 3 and 7 (A/B) and 7 and 12 (C/D), and subtelomeric FISH for chromosome 7(E/F). The bottom row of images are the same FISH images shown in the top row but with inverted DAPI stain. The chromosomes involved in the CCR are depicted by red arrows. A/B: WCP3 (green) paints the normal chromosome 3 part of the der (3) and der (12); WCP7 (red) paints the normal chromosome 7, part of der (7), and the inserted part in der (3). C/D: WCP12 (green) paints the normal chromosome 12, part of der (12), translocated part to der (3), and translocated part to der (7); WCP7 (red) paints the normal chromosome 7 and part of der (7) and inserted part to der (3). E/F: Subtelomeric 7p (green) and 7q (red) are shown in the normal chromosome 7. The subtelomeric 7p probe of the other chromosome 7 is located on der (3) after translocation to chromosome 12.

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Molecular Cytogenetics

ISSN: 1755-8166