Figure 1

Different level SOX2 (a, b, c, d) and TERC gene (e, f, g, h) amplifications was shown in representative cells. The FISH pattern CEP3 : SOX2 was 2 : >4 (a). Masive amplifications of SOX2 gene (b). Polyploidies and amplifications of SOX2 gene (c). Polyploidies of S0X2 gene in pattern 9:9. Polyploidies and amplifications of TERC gene (e, f). Polyploidies of TERC gene (g, h). Patches of amplifications of TERC gene in polyploid cell pointed by arrow (g).