Table 3 Diseases or functions associated with the networks constructed from genes in the amplified region
Diseases or functions annotation | p-values | Molecules | # molecules |
|---|---|---|---|
Prader-Willi syndrome | 4.69E-10 | GABRG3,MAGEL2,MKRN3,NDN,SNRPN | 5 |
Absence seizure | 5.59E-09 | GABRA5,GABRB3, GABRG1*,GABRG3,UBE3A | 5 |
Tonic-clonic seizure | 2.07E-07 | GABRA5,GABRB3, GABRG1*,GABRG3,UBE3A | 5 |
Multiple congenital anomalies | 4.32E-06 | GABRB3,GABRG3,MAGEL2,MKRN3,NDN,PEX10*,SNRPN,UBE3A | 8 |
Stroke | 3.14E-05 | GABRA5,GABRB3,GABRG1*,GABRG3,TP53* | 5 |
Epileptic seizure | 5.60E-05 | GABRA5,GABRB3,GABRG1*,GABRG3,UBC* | 5 |
Major depression | 1.52E-04 | GABRA5,GABRB3, GABRG1*,GABRG3,IBTK* | 5 |
Amyotrophic lateral sclerosis | 3.77E-04 | GABRA5,GABRB3, GABRG1*,GABRG3,TP53* | 5 |
Schizophrenia | 4.37E-04 | AP1G1*,GABRA5,GABRB3, GABRG1*,GABRG3,NDN, TP53* | 7 |
Parkinson's disease | 5.57E-04 | GABRA5,GABRB3, GABRG1*,GABRG3, TP53* | 5 |
Seizures | 6.96E-04 | GABRA5,GABRB3, GABRG1*,GABRG3,UBC*,UBE3A | 6 |
Congenital anomaly of skeletal bone | 1.40E-03 | GABRA5,GABRB3, GABRG1*,GABRG3, TP53* | 5 |
Weight gain | 1.82E-03 | AP1G1*,GABRA5,GABRB3, GABRG1*,GABRG3 | 5 |
Bleeding | 9.51E-03 | GABRA5,GABRB3, GABRG1*,GABRG3,TP53* | 5 |