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Figure 3 | Molecular Cytogenetics

Figure 3

From: Short stature, digit anomalies and dysmorphic facial features are associated with the duplication of miR-17 ~ 92 cluster

Figure 3

Pedigree: The proband (III4) has five half-brothers (III1, III2, III3, III5 and III6) resulting from his mother’s four different marriages. The proband (III4), his mother (II4) and one of his half-brothers (III3) harboring a 516 kb duplication at 13q13.3 (red small circle) showed dysmorphic facial features, lower facial weakness, and relative macrocephaly (blue square) as well as digit anomalies including clinodactyly, brachydactyly, and short stature (green square). Developmental delay (red square) and autism (Yellow Square) were observed in all six brothers. The mother showed all of the above abnormalities except autism.

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