Establishment of a molecular cytogenetic analysis for native tumor tissue of meningiomas-suitable for clinical application

Table 1 Comparison of the chromosomal aberrations detected by fluorescence in situ hybridization in native tumor tissue (dapped slides), and in vitro cell culture with classic cytogenetic findings

Case	Primary cell culture growing period [Days]	FISH dapped slides						FISH cell culture						Cytogenetic
Case	Primary cell culture growing period [Days]	1p	22	9p	10	14	18	1p	22	9p	10	14	18	1p	22	9p	10	14	18	Additional aberrations
T6801	15	1	1	0	-	0	1	1	1	0	-	1	1	0	1	0	0	0	1	0
T6805	7	0	1	0	-	0	0	0	1	0	-	0	0	0	1	0	0	1/2	0	1
T6815	13	1	1	0	-	1	0	0	0	0	-	1	0	0	1	0	0	0	0	0
T6821	11	0	0	0	-	0	0	0	0	0	-	0	0	0	0	0	0	0	0	0
T6849	18	0	0	0	-	0	0	0	0	0	-	0	0	-	-	-	-	-	-	-
T6852	25	1	1	0	0	0	0	1	1	0	0	0	0	0	0	0	0	0	0	0
T6855	32	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
T6856	17	0	0	0	0	1	1	0	0	0	0	0	0	-	-	-	-	-	-	-
T6857	13	0	1	0	0	0	0	0	1	0	0	0	0	0	1	0	1	1	1	1
T6858	38	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
T6860	21	-	-	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1
T6861	21	0	1	0	0	0	0	0	1	0	0	0	0	0	1	0	1	0	0	1
T6863	15	0	1	0	0	0	0	0	1	0	0	0	0	0	1	0	0	0	0	0
T6886	18	1	1	-	-	-	-	1	1	0	0	0	0	0	1	0	0	0	0	1
T6889	31	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
T6894	14	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
T6922	9	0	0	1	0	0	0	0	0	1	0	0	0	-	-	-	-	-	-	-
T6926	13	0	1	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	0	1
T6927	15	0	1	2	2	2	0	0	1	0	0	0	0	0	0	0	0	0	0	0
T6930	18	1	0	0	0	0	0	1	0	0	0	0	0	-	-	-	-	-	-	-
T6934	11	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
T6940	20	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
17,95		5	10	2	1	3	2	4	9	1	0	2	1	0	7	0	2	2	2

ISSN: 1755-8166