Figure 2From: Polyploidy in myelofibrosis: analysis by cytogenetic and SNP array indicates association with advancing diseaseAbnormalities detected by SNPa on chromosome 6p. SNPa profiles showing changes in B allele frequency (blue) and LogR ratio (red) on three cases with abnormalities on 6p. Segments showing CN-LOH are denoted by an arrow. From top: Case no. 3, deletion of terminal 6p on the der(6)t(1;6) flanked by a region of CN-LOH; Case no. 20, regions of mosaic CN-LOH occurring at the terminal end as well as interstitially, and Case no. 22, complex changes involving regions of both deletion and amplification from 6p24.1 to 6q14.Back to article page