Table 2 Evolutionary conserved breakpoints in TCR chromosomes compared to HSA; the positions are analyzed concerning their location in GTG-light bands, colocalization with human fragile sites and breakpoints observed in HLA and GGO using MCB-approach
HSA chr. | Evolutionary conserved breakpoints including neo-centromere and heterochromatin positions | GTG- light band | Fragile site in same band | Same breakpoint in HLA [Mrasek et al., 2003[13]] | Same breakpoint in GGO [Mrasek et al., 2001[12]] |
|---|---|---|---|---|---|
1 | 1p22 | + | FRA1D | - | - |
1q22 | - | - | - | - | |
1q24 | - | - | + | - | |
1q41 | - | FRA1R | - | - | |
2 | 2p25.3 | - | FRA2M | - | - |
2q14.1 | - | FRA2 | - | + | |
2q21 | + | FRA2F | - | ?+ | |
2q24.2 | + | FRA2T | + | - | |
2q31 | + | FRA2G | - | - | |
3 | 3p26.3 | - | FRA3E | - | - |
3p25 | + | FRA3F | - | - | |
3p23 | + | - | - | - | |
3p21.3 | + | FRA3H | ?+ | - | |
3p14 | - | FRA3B | ?+ | - | |
3q22 | - | FRA3N | ?+ | - | |
3q25 | + | FRA3D | + | - | |
3q26 | - | FRA3O | - | - | |
3q28 | - | FRA3P | - | - | |
4 | 4p12 | + | FRA4H | - | + |
4q22 | - | FRA4F | - | - | |
5 | 5p15.2 | - | FRA5H | - | - |
5q11.2 | + | FRA5I | ?+ | - | |
5q21 | - | FRA5F | - | - | |
5q31.2 | - | FRA5C | - | - | |
5q35.3 (a) | + | FRA5G | - | + | |
5q35.3 (b) | + | FRA5G | - | + | |
6 | 6p25.3 | + | - | - | - |
6p21 | + | FRA6H | - | - | |
6q15 | + | FRA6G | + | - | |
6q21 | + | FRA6F | - | - | |
7 | 7p22.3 | + | FRA7B | + | - |
7p15.3 | + | - | - | - | |
7q11.1 | - | FRA7A | - | - | |
7q11.23 | + | FRA7J | - | + | |
9 | 9p34.2 | - | - | - | - |
9q24.3 | + | - | - | - | |
9q33 ~ 34.1 | - | FRA9M | - | - | |
10 | 10p15.3 | + | FRA10H | - | - |
10p11.2 | + | FRA10J | - | ?+ | |
10p11.1 | - | - | - | - | |
10q11.1 | - | FRA10G | - | - | |
| Â | 10q21.1 | - | FRA10C | + | - |
10q22.3 | + | FRA10D | ?+ | + | |
11 | 11p15.4 | - | - | - | - |
11p15.3 | + | FRA11J | - | - | |
11q12 | - | - | + | - | |
12 | 12p13.33 | + | FRA12F | - | - |
13 | 13q12.1 | + | - | - | - |
13q14 | + | FRA13G | ?+ | - | |
13q32 ~ 33 | + | FRA13D | + | - | |
14 | 14q11.2 | + | FRA14D | ?+ | + |
15 | 15q11.2 | + | FRA15C | ?+ | - |
15q26.1 ~ 26.2 | + | FRA15G | ?+ | - | |
16 | 16p13.1 | + | FRA16H | + | - |
17 | 17p11.1 | - | FRA17C | ?+ | - |
17q21.3 | + | FRA17D | ?+ | - | |
17q24 | - | FRA17E | + | - | |
18 | 18q21 | + | FRA18B | - | - |
19 | 19p13.2 | - | - | ?+ | - |
19q13.2 | - | - | + | - | |
19q13.43 | - | - | ?+ | - | |
20 | 20p12 | - | FRA20B | - | - |
20p11.1 | - | - | - | - | |
20q11.1 | - | FRA20D | - | - | |
21 | 21q11.2 | + | FRA21 | ?+ | - |
22 | 22q11.21 | + | - | ?+ | - |
Y | Yp11.31 | - | - | - | - |
Yp11.2 | + | - | - | - | |
Yq11.23 | + | - | - | - |