Molecular Cytogenetics

Table 1 The signal strength of the telomere and centromere probes after an 18-hour hybridization period at varying temperatures and conditions were rated as absent, poor, fair or strong

From: Direct DNA and PNA probe binding to telomeric regions without classical in situ hybridization

Probes	Goat Serum			Formaldehyde			FISH
Probes	4°C	RT	37°C	4°C	RT	37°C	FISH
TelC	Strong	Strong	Strong	Strong	Strong	Strong	Strong
TelG	Poor HB	Fair	Strong	Poor HB	Fair	Strong	Strong
CENPB Box	Absent	Poor	Strong	Fair	Strong	Strong	Strong
Cent	Absent	Absent	Absent	Absent	Absent	Absent	Strong

High background was indicated as, HB, frequently found accompanying that signal only at the specified conditions. FISH indicates the traditional FISH protocol was used.

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ISSN: 1755-8166

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