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Figure 4 | Molecular Cytogenetics

Figure 4

From: A case of acute myeloid leukemia (AML) with an unreported combination of chromosomal abnormalities: gain of isochromosome 5p, tetrasomy 8 and unbalanced translocation der(19)t(17;19)(q23;p13)

Figure 4

Analysis of the derivative chromosome 19. (A) Partial GTG-banded karyogram showing a normal and a derivative chromosome 19 (left- and right-hand side, respectively). The arrow points to the additive band from 17q23. (B) Metaphase-FISH analysis using the E2A gene specific break-apart probe (green, D19S883; red, RH98588), which shows two normal fusion signals on both chromosomes. The arrow points to the additive chromosomal material on the derivative chromosome 19, which is illuminated by the DAPI counterstain.

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Molecular Cytogenetics

ISSN: 1755-8166