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Figure 1 | Molecular Cytogenetics

Figure 1

From: A case of acute myeloid leukemia (AML) with an unreported combination of chromosomal abnormalities: gain of isochromosome 5p, tetrasomy 8 and unbalanced translocation der(19)t(17;19)(q23;p13)

Figure 1

Partial karyograms of clonal evolution. GTG-banded partial karyograms of all the involved chromosomes show the step-wise clonal evolution from trisomy 8 to tetrasomy 8, gain of i(5)(p10) and derivative chromosome(s) 19 in the predominant sideline 1 at diagnosis, at first and second relapse (upper panel). The lower panel depicts sideline 2 with trisomy 8, monosomy 13, a derivative chromosome 19 and three marker chromosomes (second relapse). Note, no other aberrant clones have been detected at the respective time points.

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