Table 3 Theoretic size of ROH for coefficient of inbreeding (F) expected from the total 2881 Mb autosomal genome (GRCh37/hg19)
Mating type | Degree of relationship | Coefficient of inbreeding (F) | Theoretic proportion of identical by decent (%) | Expected ROH size and range (Mb) |
|---|---|---|---|---|
Parent–child/brother-sister | 1st | 1/4 | 25 | 720 (540 ~ 1080) |
Uncle-niece/aunt-nephew/double half cousins | 2nd | 1/8 | 12.5 | 360 (270 ~ 539) |
First cousins/half uncle-niece | 3rd | 1/16 | 6.25 | 180 (135 ~ 269) |
Half first cousins/first cousins once removed | 4th | 1/32 | 3.125 | 90 (68 ~ 134) |