Figure 1

The 17 here detected variants of chromosome 9 heteromorphisms and the normal variant (right lower edge, ‘normal #9’) are depicted in 18 frames. Each frame shows from left to the right: inverted DAPI-banding pattern of the corresponding chromosome 9 variant, the same chromosome with FISH-signals using the 9het-mix, a schematic depiction of the FISH-result and a short description of the sizes and color intensities of the different FISH-signals. The alpha-satellite probe is labeled in green, midi18 in blue and midi36 in yellow. In the normal variant the two midi36 signals have an equal size (i.e. yellow under-laid “p = q”) and both midi36 signals have the equal size like the midi18 signal (i.e. yellow under-laid “p + q” equals the blue square). Further abbreviations of the latter short description: ‘>’ = larger in size; ‘<’ smaller in size; dark yellow or green color in square = weak signal; ‘*’ = strong signal; ‘2x’, ‘3x’ or ‘4x’= corresponding signal is present two, three or four times.