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Figure 1 | Molecular Cytogenetics

Figure 1

From: A recurrent translocation is mediated by homologous recombination between HERV-H elements

Figure 1

High-resolution array CGH reveals the breakpoints of the unbalanced translocation from patient 18q-146C. (a) The recurrent translocation occurs between 4q35.1 and 18q22.3, as indicated by the boxed chromosome bands. (b) The 6.97-Mb loss of 18q and (c) the 7.30-Mb gain of the end of 4q are shown. Averaged log2 ratios of probe signal intensities are shown (black dots). Dashed lines indicate log2 ratios of -1, 0, and +1. Similar array CGH results were obtained from patient 18q-82C's translocation.

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