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Table 1 Changes in cytogenetic profile of BAR-T cell line due to chronic intermittent acid and bile (pH4) exposure

From: Prolonged exposure to acid and bile induces chromosome abnormalities that precede malignant transformation of benign Barrett’s epithelium

 

Chr #

(−Y)

add(7p)

i(8)(q10)

t(10;16)

dup(11q)

(+19)

(+20)

BAR-T A+B 18 wks

46,47

(+) 2/14

(+) 12/14

(+)

(+) 2/14

(+) 1/14

 

(+) 7/14

BAR-T A+B 27 wks

47

(+)

 

(+)

(+)

(+)

(+)

(+)

BAR-T A+B 48 wks

47

(+)

 

(+)

(+)

(+)

(+)

(+)

BAR-T A+B 65 wks

47

(+)

 

(+)

(+)

(+)

(+)

(+)

BAR-T A+B 78 wks

47

(+)

 

(+)

(+)

(+)

(+)

(+)

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Molecular Cytogenetics

ISSN: 1755-8166