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Table 1 Aberrations in 11 patients >1 Mb based on array-CGH findings

From: Chromosomal Aberrations in ETV6/RUNX1-positive Childhood Acute Lymphoblastic Leukemia using 244K Oligonucleotide Array Comparative Genomic Hybridization

Case No.

Gain

Loss

Size (Mb)

1

amp(4)(q31.1)

 

1.2

amp(4)(q31.3)

 

3.1

amp(4)(q35.1-q35.2)

 

4.2

amp(18)(q11.2-q23)

 

58.5

 

del(5)(q13.2)

1.8

 

del(12)(q13.33)

19.4

2

 

del(6)(q26-q27)

1.7

 

del(12)(p13.2-p11.2)

16.6

3

amp(15)(q11.2)

 

1.4

amp(X)(q28)

 

2.1

 

del(12)(p13.2-p13.1)

3.7

4

amp(8)(q23.3-q24.3)

 

32.2

 

del(30(q11.2-q12.3)

5.1

 

del(6)(p21.31-p21.2)

1.0

 

del(6)(q14.1-q27)

90.8

 

del(6)(p25.1-q26)

13.1

 

del(9)(p24.2-p24.1)

4.2

 

del(9)(p22.1 - p21.3)

2.4

 

del(14)(q22.2 - q23.1)

4.2

 

del(14)(q24.1 - q24.3)

6.4

 

del(15)q11.2

1.3

5

 

del(1)q31.1 - q31.2

4.0

 

del(1)q31.3

2.4

 

del(1)q42.2 - q43

4.8

 

del(3)p25.1 - p24.3

3.1

 

del(3)q26.1

5.6

 

del(4)q32.3

2.2

 

del(5)q21.1 - q23.3

26.1

 

del(6)p22.1 - p21.33

2.8

 

del(6)q15 - q22.2

27.6

 

del(6)q25.2 - q26

11.2

 

del(6)q25.3

2.5

 

del(8)q21.13 - q21.2

2.4

 

del(8)q23.2 - q23.3

4.9

 

del(12)p13.2 - p12.3

4.4

 

del(12)q21.1

2.9

 

del(12)q21.31 - q21.32

3.2

 

del(13)q21.31 - q21.33

3.1

 

del(13)q21.31 - q21.33

10.6

 

del(13)q31.1 - q31.3

9.1

6

amp(X)q11.1 - q28

 

91.0

 

del(6)q14.1 - q27

91.2

 

del(9)p21.3

1.5

7

amp(10)q11.21 - q11.22

 

2.4

amp(15)q11.2

 

1.3

 

del(9)p21.3

3.1

8

No gross imbalances

  

9

amp(X)p22.31

 

1.6

10

No gross imbalances

  

11

 

del(7)q31.1-q31.32

15.8

 

del(13)q14.2-q21.33

24.9

 

del(Y)q11.221-q11.23

10.1

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Molecular Cytogenetics

ISSN: 1755-8166